Research Library

Curated Studies & Clinical Data

A growing library of peer-reviewed studies, clinical trial data, and systematic reviews organized by compound. Every citation is linked to its primary source.

1548Curated Studies
32Compounds Covered
32Clinical Trials
687Journals Referenced
PRECLINICAL / IN VIVO

PET Imaging of Dual GLP-1R and GIPR Targeting with [18F]AlF-NOTA-Asp2-Tirzepatide

Tudi K, Jie Z, Chen Z, et al.

Molecular pharmaceutics;23(11):5620-5629

tirzepatide
PRECLINICAL / IN VIVO

Combined time-restricted feeding and resistance training enhance tirzepatide-induced improvements in adiposity and whole-body insulin sensitivity in female mice

Macêdo APA, da Conceição de Mattis LR, de Lima RD, et al.

The Journal of physiology, 2026

GLP-1 tirzepatide
PRECLINICAL / IN VIVO

Continued CagriSema treatment preserves weight loss by reducing energy intake and maintaining energy expenditure in rats

Petersen LM, Knop FK, le Roux CW, et al.

Molecular metabolism, 2026;:102464

Cagrilintide Semaglutide
PRECLINICAL / IN VIVO

GLP-1 receptor activation attenuates chronic migraine-like behaviour: Sex-specific modulation of opioid- and endocannabinoid-related pathways

Sićović K, Nastić K, Dinić M, et al.

British journal of pharmacology, 2026

GLP-1 Semaglutide
PRECLINICAL / IN VIVO

The GLP-1 receptor agonist semaglutide reduces alcohol consumption and anxiety-like behaviors during withdrawal in Marchigian Sardinian alcohol-preferring rats

Palmisano M, Mrizak H, Gonzalez AE, et al.

Neuropharmacology, 2026;:111240

GLP-1 Semaglutide
PRECLINICAL / IN VIVO

Paracrine TMSB4X signaling from oligodendrocytes promotes diffuse glioma dissemination

Chai KM, Tsai CH, Lin MY, et al.

Oncogene, 2026

thymosin
PRECLINICAL / IN VIVO

Semaglutide and Tirzepatide Suppress Hepatic Fatty Acid Uptake and Fatty Acid β-Oxidation in High-Fat Diet-Induced Obesity Mice

Patel D, Ewida H, Tareq S, et al.

Journal of proteome research;25(10):5418-5429

GLP-1 Semaglutide tirzepatide
PRECLINICAL / IN VIVO

Butyrate enhances the obesity reduction effect of Semaglutide

Huang Y, Gu K, Li C, et al.

Neuroendocrinology, 2026;:1

Oxytocin Semaglutide
PRECLINICAL / IN VIVO

Transient Adipose Inflammatory Remodeling during High-Dose Semaglutide-Induced Weight Loss and Regain

Seo M, Julietta V, Averia M, et al.

Endocrinology and metabolism (Seoul, Korea), 2026

Semaglutide
PRECLINICAL / IN VIVO

Poly(vinyl alcohol) dissolving microneedles for transdermal semaglutide delivery and anti-obesity therapy in rats

Cheng X, Wang F, Liu H, et al.

International journal of pharmaceutics, 2026;:127576

Semaglutide
PRECLINICAL / IN VIVO

Semaglutide Remodels the Gut Microbiome Beyond Its Appetite-Suppressing Action: Sex-Specific Gut-Brain Axis Implications

Byun S, Sotzen MR, Bento MT, et al.

Comprehensive physiology, 2026;16(5):e70286

GLP-1 Semaglutide
PRECLINICAL / IN VIVO

Chronic Intermittent Hypoxia and MASLD in Obstructive Sleep Apnea: A Critical Appraisal of Mechanistic and Causal Evidence

Cebuc Simeanu GM, Dragne IG, Mitrea A, et al.

International journal of molecular sciences, 2026;27(20)

GLP-1 Semaglutide tirzepatide
PRECLINICAL / IN VIVO

Gut-derived glucagon-like peptides attenuate T cell-induced intestinal injury

Koehler JA, Baggio LL, Cao X, et al.

Cell reports. Medicine, 2026;:103115

GLP-1 Semaglutide
PRECLINICAL / IN VIVO

Mechanistic benchmarking of SNAC, DDM, and LLC reveals enhancer-dependent pathways for intestinal semaglutide delivery

Yuan B, Sui Y, Li H, et al.

Journal of controlled release : official journal of the Controlled Release Society, 2026;:115455

L-Carnitine Semaglutide
PRECLINICAL / IN VIVO

Pharmacy students’ knowledge and attitudes regarding GLP-1 receptor agonist adverse effects in obesity management: a cross-sectional study

Khojah AA, Gazzaz MJ, Aldurdunji MM, et al.

The Libyan journal of medicine, 2026;21(1):2749899

GLP-1
PRECLINICAL / IN VIVO

Retatrutide treatment in streptozotocin-induced diabetic rats: renal inflammatory cytokines, HIF‑1α expression, and histopathological injury profile

Keskin U, Altın E, Özatik FY, et al.

Journal of molecular histology, 2026;57(6)

retatrutide
PRECLINICAL / IN VIVO

The Power of Two: Harnessing Dual Glucagon and Incretin Signaling for Treatment of Obesity and Metabolic Dysfunction-Associated Steatohepatitis-A Narrative Review with a Translational Focus

Ard JD, Almandoz JP

Obesity reviews : an official journal of the International Association for the Study of Obesity, 2026;:e70228

GLP-1 Semaglutide
PRECLINICAL / IN VIVO

Semaglutide, Other GLP-1 Receptor Agonists, and Papillary Thyroid Carcinoma: A Narrative Review of Risk, Progression, and Mechanisms

Barseghyan L, Munir I, Chrysafide S, et al.

Journal of clinical medicine, 2026;15(20)

GLP-1 Semaglutide
PRECLINICAL / IN VIVO

Development and validation of qualitative methods for the detection of GLP-1 receptor agonists in serum and dried blood spots by LC-HRMS/MS for doping control purposes

Borschel L, Thomas A, Studer D, et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2026;1285:125326

GLP-1 Semaglutide tirzepatide
PRECLINICAL / IN VIVO

Correction to: Differential effects of semaglutide and colchicine on atrial remodeling in rats with reduced ejection fraction after myocardial infarction

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology;28(10)

Semaglutide

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