Research Library

Curated Studies & Clinical Data

A growing library of peer-reviewed studies, clinical trial data, and systematic reviews organized by compound. Every citation is linked to its primary source.

1093Curated Studies
28Compounds Covered
18Clinical Trials
550Journals Referenced
PRECLINICAL / IN VIVO

OAF Blocks SIAH1-Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Li Z, Song J, Ma K, et al.

Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026;:e77451

Semaglutide
SYSTEMATIC REVIEW

Effects of subcutaneous semaglutide on weight loss and inflammatory markers in adults with overweight or obesity without diabetes: a systematic review and meta-analysis

Milluzzo A, Oteri V, Manuella L, et al.

International journal of obesity (2005), 2026

Semaglutide
STUDY

Drug failure in diabetic kidney disease: translational barriers, target validation and trial de-risking strategies

Hu H, Hou S, Chen W, et al.

Biochemical pharmacology, 2026;:118405

Semaglutide
STUDY

Effects of semaglutide and empagliflozin on markers of endothelial function in persons with type 2 diabetes: A post hoc analysis of a randomized clinical trial

Gullaksen S, Vernstrøm L, Sørensen SS, et al.

Journal of diabetes and its complications, 2026;40(10):109397

Semaglutide
STUDY

Comparative effectiveness of GLP-1 receptor agonists versus mineralocorticoid receptor antagonists as fourth-line pharmacological therapy in patients with resistant hypertension and overweight or obesity: a retrospective multicenter cohort study in the USA

Tian Z, Willerding JM, Schmidt-Ott KM, et al.

EClinicalMedicine, 2026;99:104176

GLP-1 Semaglutide tirzepatide
STUDY

Semaglutide in Japanese participants with metabolic dysfunction-associated steatohepatitis: a subgroup analysis of the ESSENCE trial

Nakajima A, Okanoue T, Hiasa Y, et al.

Journal of gastroenterology, 2026

Semaglutide
STUDY

Dramatic Improvement of Treatment-Refractory Prurigo Nodularis Following Initiation of Semaglutide: A Case Report

Fougerousse AC

Clinical, cosmetic and investigational dermatology, 2026;19:606727

GLP-1 Semaglutide
STUDY

Oral small-molecule GLP-1 receptor agonists: a new Frontier in cardiometabolic medicine

Guo J, Chen H

Frontiers in pharmacology, 2026;17:1933018

GLP-1 Semaglutide
STUDY

Case Report: Tirzepatide improves glycemic control in Rabson-Mendenhall syndrome

Araújo-Vilar D, Vela A, Castro AI, et al.

Frontiers in endocrinology, 2026;17:1945251

tirzepatide
STUDY

Data and Temporal Risk Concerns of Semaglutide and NAION-Reply

Heberer KR, Bress AP, Lee JS

JAMA ophthalmology, 2026

Semaglutide
STUDY

Data and Temporal Risk Concerns of Semaglutide and NAION

Yu CH

JAMA ophthalmology, 2026

Semaglutide
STUDY

Effects of Semaglutide versus Bariatric Surgery on Noninvasive Markers of Hepatic Steatosis and Fibrosis in Obesity with MASLD

Lünswilken P, Worobiec K, Braun LS, et al.

The Journal of clinical endocrinology and metabolism, 2026

Semaglutide
STUDY

Transcriptomic Changes Elicited by Semaglutide in Human Ventricular Tissue Support Cell Survival and Lipid Metabolism

Underwood L, Jiang CS, Bhatti R, et al.

Circulation. Heart failure, 2026;:e014421

Semaglutide
STUDY

Tirzepatide as a possible trigger of bullous pemphigoid: A case report

Hernández Madrid P, Gotor Rivera A, Alejo Fernández-Baillo JL, et al.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2026

tirzepatide
STUDY

From adiposity to multisystem morbidity: the case for weight loss as disease modification

Sattar N, Ferguson LD, Lee MMY

The lancet. Diabetes & endocrinology, 2026

Semaglutide tirzepatide
STUDY

Comparative efficacy and safety of glucagon-like peptide 1 based drugs for weight loss in adults with overweight or obesity without diabetes: network meta-analysis of randomised controlled trials

Chen D, Ma B, Sun H, et al.

BMJ medicine, 2026;5(1):e003026

Cagrilintide GLP-1 retatrutide Semaglutide tirzepatide
STUDY

Reporting patterns of suicide- and self-injury-related events involving liraglutide, semaglutide, and tirzepatide: data from the European pharmacovigilance database

Scavone C, Cerasuolo M, Gaio M, et al.

Frontiers in pharmacology, 2026;17:1882225

GLP-1 Semaglutide tirzepatide
STUDY

Estimating treatment effects in clinical studies of Alzheimer’s disease: What are estimands and why do we need them?

Hendrix S, Mallinckrodt C, Abschneider RM, et al.

Alzheimer's & dementia : the journal of the Alzheimer's Association;22(8):e71676

Semaglutide
SYSTEMATIC REVIEW

Body Composition and Lifestyle Interventions in Pharmacological Treatment of Acquired Hypothalamic Obesity: A Systematic Review of Randomized Controlled Trials

Yu H, Wang J, Yin M, et al.

Obesity (Silver Spring, Md.);34(9):1687-1698

Semaglutide
PRECLINICAL / IN VIVO

IDE-mediated GLP-1 degradation as the basis for designing long-acting and CNS-stable GLP-1 receptor agonists

Zhang L, Liu X, Si C, et al.

Science advances, 2026;12(35):eaeh4670

GLP-1 Semaglutide

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