Research Library

Curated Studies & Clinical Data

A growing library of peer-reviewed studies, clinical trial data, and systematic reviews organized by compound. Every citation is linked to its primary source.

1103Curated Studies
28Compounds Covered
19Clinical Trials
555Journals Referenced
PRECLINICAL / IN VIVO

Tirzepatide, a dual GIP/GLP-1 receptor agonist, attenuates endothelial dysfunction and angiotensin II-induced abdominal aortic aneurysm in ApoE-/- mice

Gómez-Martín Á, Marques P, Arce-Recatalá C, et al.

Pharmacological research, 2026;:108321

GLP-1 tirzepatide
PRECLINICAL / IN VIVO

Development and Validation of a Liquid Chromatography/Tandem Mass Spectrometry Method for the Quantification of the GLP-1 Analog Semaglutide in Rat Plasma, and Its Application in a Pharmacokinetic Study

Kim JM, Kim KA, Yu NY, et al.

Pharmaceutics, 2026;18(7)

GLP-1 Semaglutide
PRECLINICAL / IN VIVO

Semaglutide alleviates osteoarthritis independent of weight loss via GLP-1R-mediated activation of autophagy through AKT/mTOR inhibition

Lin J, Luo M, Tang H, et al.

Journal of orthopaedic translation, 2026;59:101166

Semaglutide
PRECLINICAL / IN VIVO

GLP-1 and Alcohol-Related Behaviors: Insights From Preclinical Studies

Jerlhag E

Biological psychiatry, 2026

GLP-1 Semaglutide
PRECLINICAL / IN VIVO

LY6D promotes hepatic steatosis via the GRB2-AMPK-SREBP1 signaling axis

Zhao Q, Chen L, Xie S, et al.

International journal of obesity (2005), 2026

Semaglutide
PRECLINICAL / IN VIVO

Dysregulation of circulating damage-associated molecular patterns in diabetic foot syndrome

Uyy E, Suica VI, Ivan L, et al.

Frontiers in immunology, 2026;17:1849387

thymosin
PRECLINICAL / IN VIVO

Functional segregation of body-brain signals in the area postrema

López-Cruz A, Figueredo Burgos NS, Hakimi AM, et al.

bioRxiv : the preprint server for biology, 2026

tirzepatide
PRECLINICAL / IN VIVO

Semaglutide exerts anti-pulmonary fibrosis effects by inhibiting cellular senescence through activation of the Sirt1/HSF1/HSPs pathway

Qian Z, Shuang L, Yu-Yang L, et al.

Biochemical pharmacology, 2026;:118172

Semaglutide
PRECLINICAL / IN VIVO

Negative effects of semaglutide on bone in obese mice

Eisner K, Jeromson S, Tahboub K, et al.

Cell reports. Medicine, 2026;:102875

Semaglutide
PRECLINICAL / IN VIVO

Reparative Outcomes in Corneal Infection: Linking Adjunctive Tβ4 Treatment to Nerve Regeneration and Visual Function

Ebrahim AS, Liu L, Carion TW, et al.

Investigative ophthalmology & visual science;67(6):22

thymosin
PRECLINICAL / IN VIVO

Perinatal Semaglutide Treatment Improves Maternal Health and Mitigates Offspring Metabolic Dysfunction in a Mouse Model of Maternal Obesity

Rajamoorthi A, Hollingsworth T, Guan Y, et al.

bioRxiv : the preprint server for biology, 2026

GLP-1 Semaglutide
PRECLINICAL / IN VIVO

Semaglutide Selectively Improves Metabolic and Cognitive Function in 5xFAD Mice

Shahabian L, Kynigopoulos D, Papacharalambous R, et al.

International journal of molecular sciences, 2026;27(12)

GLP-1 Semaglutide
PRECLINICAL / IN VIVO

Semaglutide-induced loss of skeletal muscle mass is blunted by co-administration of ketone esters

Abuetabh Y, Schmidt MA, Naganuma M, et al.

JCI insight, 2026

Semaglutide
PRECLINICAL / IN VIVO

Semaglutide attenuates neuroinflammation in male mice

Belmont-Rausch DM, Ludwig MQ, Bentsen MA, et al.

Nature communications, 2026

Semaglutide
PRECLINICAL / IN VIVO

Changes of Transcriptomic Activity in Rat Brain Cells under the Influence of Synthetic Adrenocorticotropic Hormone-Like Peptides

Filippenkov IB, Glazova NY, Sebentsova EA, et al.

Biochemistry. Biokhimiia;89(9):1643-1656

semax
PRECLINICAL / IN VIVO

A cross-species atlas of the dorsal vagal complex reveals neural mediators of the effects of cagrilintide on energy balance

Ludwig MQ, Coester B, Gordian D, et al.

Nature metabolism, 2026

Cagrilintide Semaglutide
PRECLINICAL / IN VIVO

The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer’s Disease

Radchenko AI, Kuzubova EV, Apostol AA, et al.

Acta naturae;17(4):110-120

semax
PRECLINICAL / IN VIVO

CCN5 suppresses injury-induced vascular restenosis by inhibiting smooth muscle cell proliferation and facilitating endothelial repair via thymosin β4 and Cd9 pathway

Zhang Q, Li H, Zhuang T, et al.

European heart journal;46(17):1645-1658

thymosin
PRECLINICAL / IN VIVO

Engineered Tandem Thymosin Peptide Promotes Corneal Wound Healing

Nguyen J, Verma S, Vuong VT, et al.

Investigative ophthalmology & visual science;66(14):31

thymosin
PRECLINICAL / IN VIVO

Thymosin β4 released by mast cells under stress conditions impairs intestinal epithelial barrier via IL22RA1/JAK1/STAT3 signaling in irritable bowel syndrome

Sun YS, Bai XQ, Sun KD, et al.

World journal of gastroenterology;31(42):111706

thymosin

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