Research Library
Curated Studies & Clinical Data
A growing library of peer-reviewed studies, clinical trial data, and systematic reviews organized by compound. Every citation is linked to its primary source.
Semaglutide, independent of weight loss, attenuates cardiac and hepatic remodelling in experimental heart failure with preserved ejection fraction
Elbatreek MH, Li Z, Yu X, et al.
European heart journal, 2026
Bidirectional Pharmacology of GIP Receptor Targeting in Obesity: Historical Foundations, Mechanistic Divergence, and Translational Boundaries
Liu C, Wang Y, Liu J, et al.
Peptides, 2026;:171524
Tirzepatide attenuates cardiac microvascular injury and ferroptosis-related lipid peroxidation in diabetic mice: endothelial responses in the context of partial PRKN silencing
Lu G, Wang X, Zhuang H, et al.
European journal of pharmacology, 2026;:179387
Effects of Blueberry and Collard Greens Dietary Intervention on Metabolic and Inflammatory Biomarkers in Zucker Obese Rats
Yeboah JA, Bradford CN, Dawkins NL
Nutrients, 2026;18(19)
The dual incretin agonist tirzepatide blunts nicotine-induced behaviours and neurochemistry in male mice
Edvardsson CE, Emous TA, Witley S, et al.
British journal of pharmacology, 2026
Chronic semaglutide treatment attenuates cue-induced reinstatement of cocaine-seeking and cocaine-induced stereotypy in male and female rats
Turner CA, Morales Pagán N, Pereira D, et al.
bioRxiv : the preprint server for biology, 2026
Suitability of the ICH S1B(R1) Weight-of-Evidence Framework to Evaluate Glucagon-Like Protein-1 Receptor Agonist (GLP-1RA) Carcinogenicity Risk
Roach KA, Khazaee M, Mohar I, et al.
Regulatory toxicology and pharmacology : RTP, 2026;:106252
An RNA thermogenic therapy to preserve lean mass and enhance metabolic health during GLP-1 weight loss
Thorne AK, Waldeck NJ, Rose JP, et al.
Proceedings of the National Academy of Sciences of the United States of America, 2026;123(40):e2618845123
Future GLP-1 receptor co-agonists and their cardiac effects
Neumann J, Kirchefer U, Hofmann B, et al.
Naunyn-Schmiedeberg's archives of pharmacology, 2026
Incretin signaling suppresses high glucose-induced β-cell hypoxia through a cAMP/PKA-dependent mechanism
Saranaruk P, Sato Y, Tsuruta M, et al.
Biochemical and biophysical research communications, 2026;838:154627
GLP-1 Receptor Agonists as Molecular Relievers of Lipotoxic Stress: From Pancreatic Beta-Cell Cholesterol Efflux to Systemic and Tissue-Specific Metabolic Protection
Jiang W, Fukunaga K, Kobayashi T, et al.
International journal of molecular sciences, 2026;27(18)
Reprogramming NAD+ homeostasis and FOXO3a-Nrf2 signaling mitigates bleomycin-driven pulmonary fibrosis
Mo'men M, Saber S, Amer AE, et al.
Toxicology and applied pharmacology, 2026;:118045
Effects of Liraglutide and Semaglutide on Cardiometabolic Dysregulation and Oxidative Stress in an Experimental Model of Metabolic Syndrome
Ravić MP, Srejović IM, Andjić MM, et al.
Medical sciences (Basel, Switzerland), 2026;14(5)
Divergent effects of semaglutide and CRV431 Co-therapy on liver fibrosis and HCC in MASLD mouse model
Goodman AZ, Stauffer WT, Gallay PA
PloS one, 2026;21(9):e0358225
GLP-1 Receptor Agonists in Pulmonary Hypertension: Mechanistic Rationale, Preclinical Evidence, and Clinical Knowledge Gaps
Allaham L, King B, Ali F, et al.
Lung, 2026;204(1)
Salcaprozate Sodium as a Permeation Enhancer-Mechanism, Applications and Unresolved Questions
Dinkov B, Koleva N, Stavreva G
Pharmaceutics, 2026;18(9)
Cagrilintide and retatrutide combination therapy enhances weight loss and metabolic outcomes in obese male rats
Petersen J, Merrild C, Holm SK, et al.
Nature metabolism, 2026
Improvement of small fiber neuropathy assessed by corneal confocal microscopy following semaglutide treatment: a case report and literature review
Anastasiou IA, Tentolouris N, Rebelos E
Hormones (Athens, Greece), 2026
Metabolic Effects of a GLP-1 Analog Combined with Aerobic Training in Ovariectomized Rats
Selau B, Bastos LM, Normann RS, et al.
Molecular and cellular endocrinology, 2026;:112917
Combination of genetic eNOS deficiency and high-fat diet induces reproducible cardiometabolic HFpEF
Elbatreek MH, Khodade V, Amin D, et al.
Redox biology, 2026;97:104394