Research Library

Curated Studies & Clinical Data

A growing library of peer-reviewed studies, clinical trial data, and systematic reviews organized by compound. Every citation is linked to its primary source.

699Curated Studies
27Compounds Covered
9Clinical Trials
401Journals Referenced
PRECLINICAL / IN VIVO

Retatrutide effects on diabetic rats’ cognition

Ferreira J

Lab animal;55(8):287

retatrutide
PRECLINICAL / IN VIVO

PYY3-36 potentiates Semaglutide‑mediated mitochondrial modulation in MASLD

Geiger N, Nickel AG, Kohlhaas M, et al.

American journal of physiology. Endocrinology and metabolism, 2026

Semaglutide
PRECLINICAL / IN VIVO

Stable pentadecapeptide therapy counteracts gentamicin-induced nephrotoxicity via nitric oxide-system modulation: evidence from a triple nitric oxide-agent approach in rats

Vukoja I, Vlainic J, Francina M, et al.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2026;77(3):377-395

PRECLINICAL / IN VIVO

AI digital pathology as a key tool providing in-depth understanding of the progression and regression of MASH and fibrosis in male mouse models

Saigal A, Abdurrachim D, Tso E, et al.

Nature communications, 2026;17(1)

Semaglutide
PRECLINICAL / IN VIVO

Therapeutic Potential of Incretin-Based Therapies for Alcohol Use Disorder – A narrative review of available clinical evidence

Klausen MK, Fink-Jensen A

Biological psychiatry, 2026

PRECLINICAL / IN VIVO

Host-directed treatments for tuberculous meningitis utilizing a multi-platform approach across mouse and human models

Ruiz-Gonzalez CE, Singh M, Masias-Leon Y, et al.

Nature communications, 2026;17(1)

Semaglutide
PRECLINICAL / IN VIVO

GLP-1 Receptor Agonists as a Candidate Treatment for Opioid Use Disorder: From rats to humans

Grigson PS, Bunce SC, Brick TR, et al.

Biological psychiatry, 2026

GLP-1 Semaglutide tirzepatide
PRECLINICAL / IN VIVO

Semaglutide promotes angiogenesis and blood-brain barrier repair after traumatic brain injury via PDGF-BB/PDGFRβ/Ang1/Tie2/VEGF signaling pathway

Shi Y, Dong X, Zhu C, et al.

Scientific reports, 2026

Semaglutide
PRECLINICAL / IN VIVO

N-terminally modified GLP1R agonists drive G protein bias via extracellular loop 3 displacement

Zhao LH, He Q, Yuan Q, et al.

Cell reports, 2026;45(7):117718

Semaglutide
PRECLINICAL / IN VIVO

Thymosin β4 alleviates sepsis-associated acute kidney injury by suppressing MAPK signaling pathway

Ouyang X, Long Z, Xu X, et al.

Clinical science (London, England : 1979);140(8):1695-1708

thymosin
PRECLINICAL / IN VIVO

Semaglutide and Exercise Synergy in Obesity: Preserving Muscle Mass and Uncovering Organ Crosstalk

Inia JA, Droog S, Snabel J, et al.

Diabetes & metabolism journal, 2026

Semaglutide
PRECLINICAL / IN VIVO

Vutiglabridin overcomes the GLP-1 RA-associated weight-loss plateau to achieve normal body weight

Lee HM, Marakkalage KG, Kim SH, et al.

International journal of obesity (2005), 2026

GLP-1 Semaglutide
PRECLINICAL / IN VIVO

The Crunchometer, a low-cost, open-source acoustic analysis of feeding microstructure

Gil Lievana E, Arroyo B, Pérez-Ortega J, et al.

eLife, 2026;14

Semaglutide
PRECLINICAL / IN VIVO

Semaglutide alters behaviour and nucleus accumbens oscillatory activity in healthy mice

Mosqueira A, Ansarifar S, Nabavi S, et al.

Molecular brain, 2026

GLP-1 Semaglutide
PRECLINICAL / IN VIVO

Tirzepatide Attenuates Wire Injury-Induced Arterial Remodeling in Non-Diabetic and Diabetic Mice: Comparison with Semaglutide

Mori Y, Osaka N, Terasaki M, et al.

Biomedicines, 2026;14(7)

GLP-1 Semaglutide tirzepatide
PRECLINICAL / IN VIVO

GLP-1 receptor agonists in multiple sclerosis: a systematic review of preclinical and clinical evidence

Sajjad M, Sajjad A, Amer R, et al.

Multiple sclerosis and related disorders, 2026;113:107388

GLP-1 Semaglutide
PRECLINICAL / IN VIVO

GLP-1 regulates osteo-adipogenic fate of BMSCs via HIF-2-AKT signaling and supports trabecular bone in glucocorticoid-induced osteoporosis

Yang Z, Li X, Wu N, et al.

Stem cell reports, 2026;:103008

GLP-1 Semaglutide
PRECLINICAL / IN VIVO

Semaglutide Modulates Visceral Adipose Tissue Lipid Metabolism in Type 2 Diabetic Mice: A Lipidomics Study

Chen X, Tu B, Li Z, et al.

Frontiers in bioscience (Landmark edition);31(6):49873

Semaglutide
PRECLINICAL / IN VIVO

Sirtuin 1 deficiency mediates chronic kidney disease-induced inflammaging cardiovascular calcification

Xu L, Zheng Y, Liu M, et al.

Molecular biomedicine, 2026;7(1)

Semaglutide
PRECLINICAL / IN VIVO

Role of GLP-1 receptor agonists in the prevention and treatment of obesity-related cancer

Muscogiuri G, Del Vecchio G, Colangeli L, et al.

Internal and emergency medicine, 2026

GLP-1

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