N-Acetyl Semax Amidate
N-Acetyl Semax Amidate is a stabilized, next-generation analog of the synthetic heptapeptide Semax, originally developed at the Russian Academy of Sciences in the 1980s. Semax is a synthetic analog of the ACTH(4–10) fragment—a portion of adrenocorticotropic hormone— engineered to retain the neurotrophic and cognitive-enhancing properties of ACTH while lacking its hormonal activity (no effect on […]
N-Acetyl Selank Amidate
N-Acetyl Selank Amidate is a stabilized, next-generation analog of the synthetic heptapeptide Selank, a tuftsin-derived neuropeptide originally developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. Selank was designed to modulate brain activity and immune function and was approved for human use by the Russian Federation Ministry of Health in 2009 […]
Orexin-A
Few neuropeptides have reshaped our understanding of the brain as profoundly as orexin-A. Since its simultaneous discovery in 1998 by two independent research groups, orexin-A has moved from an obscure hypothalamic signaling molecule to one of the most intensively studied neuropeptides in neuroscience. It sits at the intersection of wakefulness, cognitive performance, energy homeostasis, stress […]
DSIP (Delta Sleep-Inducing Peptide)
Delta sleep-inducing peptide (DSIP) is a naturally occurring neuropeptide first isolated in 1974 by the Swiss Schoenenberger-Monnier research group from the cerebral venous blood of rabbits in an induced state of slow-wave sleep. It is a nonapeptide—a small peptide consisting of nine amino acids—with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. DSIP gained attention for its apparent ability to […]
Dihexa
Introduction and Overview Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide), also known by its developmental code name PNB-0408, is a small synthetic oligopeptide derived from angiotensin IV that represents a novel approach to cognitive repair and neuroprotection. Unlike traditional nootropics that primarily stimulate neurotransmitter activity, Dihexa is investigated for its potential ability to influence the structural connectivity of […]
Cerebrolysin
Introduction and Overview Cerebrolysin is a peptide-based neurotrophic compound that has been studied for decades in Europe and other parts of the world for its effects on brain function, neuronal resilience, and cognitive recovery. Unlike single-target compounds, Cerebrolysin is a complex mixture of low- molecular-weight peptides and free amino acids derived from porcine (pig) brain […]
BioMind
BioMind is a multi-compound research formulation developed for preclinical investigation into neuroprotection, synaptic plasticity, mitochondrial function, and cognitive resilience. It combines three well-studied neuroactive research compounds—J-147, Dihexa, and Noopept—each of which targets a distinct but complementary aspect of neuronal biology. The formulation is designed to support mechanistic research, not clinical application, by allowing investigators to […]
Selank
Selank is a synthetic heptapeptide with the amino acid sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP). It was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences in cooperation with the V.V. Zakusov Scientific Research Institute of Pharmacology. The peptide is a metabolically stable analog of tuftsin, a naturally occurring tetrapeptide (Thr- Lys-Pro-Arg) found in […]
Semax
Semax is a synthetic peptide derived from a fragment of adrenocorticotropic hormone (ACTH). Developed at the Russian Academy of Sciences in the 1980s, it has been used as a prescription medication in Russia for decades to treat stroke, traumatic brain injury, cognitive decline, and optic nerve disorders. Unlike many nootropics that work through stimulation, Semax […]
9-ME-BC
9-Methyl-β-carboline (9-Me-BC) is a synthetic heterocyclic amine belonging to the β-carboline family of compounds. It is a methylated derivative of β-carboline (norharmane), bearing a single methyl group at the N9…